Avilomid(Temozolomide) 5 Cap

<ul> <li dir=\"ltr\" style=\"text-align: left;\">Store the product at a temperature of less than 30 ° C</li> <li dir=\"ltr\" style=\"text-align: left;\">Store the product away from moisture and light</li> <li dir=\"ltr\" style=\"text-align: left;\">Keep the product out of the reach of children</li> </ul>

<p dir=\"ltr\" style=\"text-align: left;\">Contact a poison control center.</p>

<ul> <li dir=\"ltr\" style=\"text-align: left;\"><strong>Central nervous system:</strong> fatigue, headache, insomnia, , depression, dizziness, memory loss</li> <li dir=\"ltr\" style=\"text-align: left;\"><strong>Skin:</strong> skin rash, alopecia</li> <li dir=\"ltr\" style=\"text-align: left;\"><strong>Gastrointestinal:</strong> diarrhea, nausea, abdominal pain, constipation, loss of appetite</li> <li dir=\"ltr\" style=\"text-align: left;\"><strong>Hematology and oncology:</strong> decreased blood cells<strong>, </strong>anemia, thrombocytopenia, neutropenia, lymphopenia</li> <li dir=\"ltr\" style=\"text-align: left;\"><strong>Local:</strong> Local edema</li> <li dir=\"ltr\" style=\"text-align: left;\"><strong>Nervous, musculoskeletal:</strong> back pain</li> <li dir=\"ltr\" style=\"text-align: left;\"><strong>Miscellaneous:</strong> fever, viral infection, UTI, weight gain</li> </ul>

<ul> <li dir=\"ltr\" style=\"text-align: left;\">Avoid using this medicine and deferiprone, influenza virus vaccine, palifermin, tofacitinib</li> <li dir=\"ltr\" style=\"text-align: left;\">Use with caution this medicine and acalabrutinib, abatacept, cholera and meningococcal vaccine, fingolimod, ofatumumab, olaparib, siponimod, trastuzumab, valproic acid</li> <li dir=\"ltr\" style=\"text-align: left;\"> In some cases, food can reduce the effect of this medicine</li> </ul>

<p style=\"text-align: left;\">   There are not enough studies in lactating women to determine the risk to the fetus, but due to the possibility of dangerous side effects, the drug is not recommended during breastfeeding</p>

<p dir=\"ltr\" style=\"text-align: left;\">FDA pregnancy category D</p>

<ul> <li dir=\"ltr\" style=\"text-align: left;\">For the best effect, take this medicine at the same time every day in relation to a meal(1 hour before or 3 hours after a meal.)</li> <li dir=\"ltr\" style=\"text-align: left;\">Use with caution in patients with kidney and liver and bleeding problems. liver enzymes and blood parameters should be controlled during treatment.</li> <li dir=\"ltr\" style=\"text-align: left;\">While using this drug avoid contact with people who have recently received live vaccines.</li> <li dir=\"ltr\" style=\"text-align: left;\">Use with caution in patients with myelosuppression.</li> </ul>

<p dir=\"ltr\" style=\"text-align: left;\">People who have symptoms of allergy to this drug</p>

<ul> <li dir=\"ltr\" style=\"text-align: left;\"><strong>Treatment of brain tumors</strong></li> </ul> <p dir=\"ltr\" style=\"text-align: left;\">Adult: 150 mg/m²PO/IV every day for 5 days (repeat at 28-day cycles.)</p> <p dir=\"ltr\" style=\"text-align: left;\">Children: Use and adjustment of doses is done by your doctor.</p>

<ul> <li dir=\"ltr\" style=\"text-align: left;\">Treatment of brain tumors</li> </ul>

<p style=\"text-align: left;\">Temozolomide is a mono-functional alkylating agent. The mechanism of Temozolomide is based on the ability of its metabolites to deposit methyl groups on DNA purine bases, and works by slowing or stopping the growth of cancer cells in body. Temozolomide may decrease the size of certain brain tumors in some patients</p>