Capecitabine 500 Tab

Category:
  • Storage{}{}{}
  • Over dosage{}{}{}
  • Side Effects{}{}{}
  • Drug Interaction{}{}{}
  • Lactation{}{}{}
  • Pregnancy{}{}{}
  • Precautions{}{}{}
  • Contraindication{}{}{}
  • Administration and Dosage{}{}{}
  • Indication{}{}{}
  • Mechanism of Action{}{}{}
Storage{}{}{}
<ul> <li dir=\"ltr\" style=\"text-align: left;\">Store the product at a temperature of less than 30 ° C</li> <li dir=\"ltr\" style=\"text-align: left;\">Store the product away from moisture and light</li> <li dir=\"ltr\" style=\"text-align: left;\">Keep the product out of the reach of children</li> </ul>
Over dosage{}{}{}
<p dir=\"ltr\" style=\"text-align: left;\">Contact a poison control center</p>
Side Effects{}{}{}
<ul> <li dir=\"ltr\" style=\"text-align: left;\"><strong>Cardiovascular:</strong> Chest pain, increased heart rate, cardiomyopathy</li> <li dir=\"ltr\" style=\"text-align: left;\"><strong>Central nervous system:</strong> Fatigue, headache, dizziness, paresthesia</li> <li dir=\"ltr\" style=\"text-align: left;\"><strong>Skin:</strong> Rash, Alopecia, Steven-Johnson syndrome, dermatitis</li> <li dir=\"ltr\" style=\"text-align: left;\"><strong>Gastrointestinal:</strong> Diarrhea, nausea, abdominal pain, vomiting, indigestion, constipation, anorexia, dehydration, dry mouth</li> <li dir=\"ltr\" style=\"text-align: left;\"><strong>Hematology and oncology:</strong> Neutropenia, thrombocytopenia, anemia, platelet reduction <strong>Miscellaneous:</strong> Fever, flu symptoms, muscle stiffness, shortness of breath, jaundice of the skin or eyes, obstruction of the tear ducts (2)</li> </ul>
Drug Interaction{}{}{}
<ul> <li dir=\"ltr\" style=\"text-align: left;\">Simultaneous use of warfarin and other coagulation drugs can increase the risk of bleeding</li> <li dir=\"ltr\" style=\"text-align: left;\">Simultaneous use of this drug with antacids accelerates the absorption of this drug</li> <li dir=\"ltr\" style=\"text-align: left;\">Simultaneous use of this drug with phenytoin increases the effect of phenytoin</li> <li dir=\"ltr\" style=\"text-align: left;\">Taking this drug along with food reduces the amount and rate of drug absorption</li> <li dir=\"ltr\" style=\"text-align: left;\">In case of gastrointestinal symptoms, discontinue the drug and see your doctor</li> <li dir=\"ltr\" style=\"text-align: left;\">This drug has serious interactions with deferiprone, erdafitinib, lefamulin, siponimod, allopurinol</li> </ul> <p dir=\"ltr\" style=\"text-align: left;\">This drug is used with diclofenac, denosumab, fingolimod, cholera vaccine, antithrombin alpha, argatroban, bivalirudin, meningococcal vaccine, terbinafine, etc. be consumed with caution</p>
Lactation{}{}{}
<p style=\"text-align: left;\">  There are not enough studies in lactating women to determine the risk to the fetus, but due to the possibility of dangerous side effects, the drug is not recommended during breastfeeding</p>
Pregnancy{}{}{}
<p dir=\"ltr\" style=\"text-align: left;\">FDA pregnancy category D</p>
Precautions{}{}{}
<ul> <li dir=\"ltr\" style=\"text-align: left;\">Take this medicine according to your doctor\'s opinion, 30 minutes after meals and at the appointed time</li> <li dir=\"ltr\" style=\"text-align: left;\">Use with caution in patients with renal failure and liver dysfunction. Therefore, during drug use, tests on liver and kidney function should be performed</li> <li dir=\"ltr\" style=\"text-align: left;\">In order to prevent bleeding, perform coagulation tests after treatment and for a while after discontinuation of treatment</li> <li dir=\"ltr\" style=\"text-align: left;\">Use with caution in elderly patients</li> <li dir=\"ltr\" style=\"text-align: left;\">Patients treated with this drug should avoid influenza virus vaccine injection</li> </ul>
Contraindication{}{}{}
<ul> <li dir=\"ltr\" style=\"text-align: left;\">People who have symptoms of allergy to this drug</li> <li dir=\"ltr\" style=\"text-align: left;\">Severe kidney failure</li> </ul>
Administration and Dosage{}{}{}
<ul> <li dir=\"ltr\" style=\"text-align: left;\"><strong>Treatment of metastatic colorectal cancer </strong></li> </ul> <p dir=\"ltr\" style=\"text-align: left;\">Adult: 1250 mg/m2 is administered orally twice a day (morning and evening) for 2 weeks. After a week of rest, the drug is administered in 3-week periods. (For 8 periods)</p> <ul dir=\"ltr\" style=\"text-align: left;\"> <li><strong>Breast cancer treatment resistant to other chemotherapy drugs </strong></li> </ul> <p dir=\"ltr\" style=\"text-align: left;\">Adult: 1250 mg/m2 is administered orally twice a day (morning and evening) for 2 weeks. After a week of rest, the drug is administered in 3-week periods (for 8 periods). If treated with docetaxel, the recommended dose of this drug is 1250 mg/m2 orally twice a day (morning and evening) for 2 weeks. After one week of rest, docetaxel is administered at a dose of 75 mg/m2 in intravenous infusion during one hour, every 3 weeks (2)</p>
Indication{}{}{}
<ul> <li dir=\"ltr\" style=\"text-align: left;\">Treatment of metastatic colorectal cancer</li> <li dir=\"ltr\" style=\"text-align: left;\">Breast cancer treatment resistant to other chemotherapy drugs</li> </ul>
Mechanism of Action{}{}{}
<p style=\"text-align: left;\">  Capecitabine has anti-neoplasm effect, after converting to 5-fluorouracil, it prevents cell division and disrupts the synthesis stages of RNA and cancer cell proteins</p>