DULOXAVI(Duloxetine 30 Cap)

<p style=\"text-align: left;\">Store below 30 ^oC. </p> <p style=\"text-align: left;\">  Protect from light and moisture.</p> <p style=\"text-align: left;\">  Keep out of rich of children.</p>

<p style=\"text-align: left;\">Contact a poison control center.</p>

<ul> <li style=\"text-align: left;\">Cardiac Disorders: <a href=\"http://www.rxlist.com/script/main/art.asp?articlekey=4741\">palpitations</a></li> <li style=\"text-align: left;\">Ear and Labyrinth Disorders: <a href=\"http://www.rxlist.com/script/main/art.asp?articlekey=6129\">vertigo</a>; ear pain and <a href=\"http://www.rxlist.com/script/main/art.asp?articlekey=5799\">tinnitus</a>.</li> <li style=\"text-align: left;\">Eye Disorders: vision blurred, <a href=\"http://www.rxlist.com/script/main/art.asp?articlekey=3007\">diplopia</a>,</li> <li style=\"text-align: left;\">Investigations: weight increased, weight decreased;</li> <li style=\"text-align: left;\">Reproductive System</li> <li style=\"text-align: left;\">Skin and Subcutaneous Tissue Disorders: cold sweat, dermatitis contact</li> </ul>

<h4 style=\"text-align: left;\">·         Inhibitors of CYP1A2 and CYP2D6</h4> <h4 style=\"text-align: left;\">·         Drugs that Interfere with Hemostasis (e.g., NSAIDs, Aspirin, and Warfarin)</h4> <h4 style=\"text-align: left;\">·         Monoamine Oxidase Inhibitors (MAOIs) duration between them must be 14 days.</h4> <h4 style=\"text-align: left;\">·         Drugs those Duloxetin decrease their elimination.</h4>

<p style=\"text-align: left;\">It is not recommended.</p>

<p style=\"text-align: left;\">FDA pregnancy category C.</p> <p style=\"text-align: left;\"><span style=\"color: #000000;\"> </span></p>

<ul> <li style=\"text-align: left;\">Allergic reaction to this drug.</li> <li style=\"text-align: left;\">Bleeding disorders-bipolar disorders- renal and hepatic disorders-epilepsy</li> <li style=\"text-align: left;\">It is forbidden driving car</li> </ul>

<ul> <li style=\"text-align: left;\">Concomitant use with MAOIs</li> <li style=\"text-align: left;\">In patients with un-controlled glaucoma.</li> </ul>

<ul> <li style=\"text-align: left;\">Duloxetine should be swallowed whole and should not be chewed or crushed, nor should the capsule be opened and its contents sprinkled on food or mixed with liquids. All of these might affect the enteric coating. Duloxetine can be given without regard to meals.</li> </ul> <h4 style=\"text-align: left;\">·        Major Depressive Disorder: Duloxetine should be administered at a total dose of 40 mg/day (given as 20 mg twice daily) to 60 mg/day (given either once daily or as 30 mg twice daily). For some patients, it may be desirable to start at 30 mg once daily for 1 week, to allow patients to adjust to the medication before increasing to 60 mg once daily.</h4> <h4 style=\"text-align: left;\">·        Generalized Anxiety Disorder: the recommended starting dose for Duloxetine is 60 mg administered once daily.</h4> <h4 style=\"text-align: left;\">·        Elderly Patients: No dose adjustment is recommended for elderly patients on the basis of age.</h4>

<ul> <li style=\"text-align: left;\">Major Depressive Disorder</li> <li style=\"text-align: left;\">Generalized Anxiety</li> <li style=\"text-align: left;\">Fibromyalgia</li> <li style=\"text-align: left;\">Diabetic peripheral Neuropathic pain</li> </ul>

<p style=\"text-align: left;\">It is potent inhibitor of neuronal serotonin and norepine reuptake and a less potent inhibitor of dopamine reuptake.</p>