Bisoprolol 2.5 Tab

<p style=\"text-align: left;\">Store below 30 ^oC</p> <p style=\"text-align: left;\">Protect from light and moisture.</p> <p style=\"text-align: left;\">Keep out of rich of children.</p>

<p style=\"text-align: left;\">Contact a poison control center</p>

<ul> <li style=\"text-align: left;\">Skin: increased sweating, Pruritus, flush, rash (2)</li> <li style=\"text-align: left;\">Musculoskeletal: arthralgia</li> <li style=\"text-align: left;\">Central Nervous System: dizziness, headache, hypoesthesia</li> <li style=\"text-align: left;\">Autonomic Nervous System: dry mouth, fatigue</li> <li style=\"text-align: left;\">Heart Rate/Rhythm: Bradycardia, chest pain, Angioedema</li> <li style=\"text-align: left;\">Psychiatric: vivid dreams, insomnia, depression</li> <li style=\"text-align: left;\">Gastrointestinal: diarrhea, nausea, vomiting</li> <li style=\"text-align: left;\">Respiratory: bronchospasm, cough, dyspnea, pharyngitis, rhinitis, sinusitis</li> </ul> <p style=\"text-align: left;\">  Edema (peripheral)</p>

<p style=\"text-align: left;\">This drug should not be combined with other beta-blocking agents. Patients receiving catecholaminedepleting drugs, such as reserpine or guanethidine, should be closely monitored, because the added beta-adrenergic blocking action may produce excessive reduction of sympathetic activity. Should be used with care when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [<a href=\"https://www.rxlist.com/consumer_verapamil/drugs-condition.htm\">verapamil</a>] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently.</p>

<p style=\"text-align: left;\">It is not recommended. Small amounts of bisoprolol fumarate (&lt; 2% of the dose) have been detected in the milk of lactating rats. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk caution should be exercised when bisoprolol fumarate is administered to nursing women.</p>

<p style=\"text-align: left;\">Pregnancy Category C</p>

<h4 style=\"text-align: left;\">·         Cardiac Failure, Peripheral Vascular Disease, Bronchospastic Disease</h4> <ul> <li style=\"text-align: left;\">Diabetes And Hypoglycemia, Thyrotoxicosis, Impaired Renal Or Hepatic Function</li> </ul>

<p style=\"text-align: left;\">Is contraindicated in patients with cardiogenic <a href=\"https://www.rxlist.com/script/main/art.asp?articlekey=5477\">shock</a>, overt cardiac failure, second or third degree AV block, and marked <a href=\"https://www.rxlist.com/script/main/art.asp?articlekey=19707\">sinus bradycardia</a>.</p>

<p style=\"text-align: left;\">The dose must be individualized to the needs of the patient. The usual starting dose is 5 mg once daily. In some patients, 2.5 mg may be an appropriate starting dose (Bronchospastic Disease)</p>

<p style=\"text-align: left;\">This drug is indicated in the management of hypertension. It may be used alone or in combination with other antihypertensive agents</p>

<p style=\"text-align: left;\">Bisoprolol is a synthetic beta₁-selective beta-adrenergic receptor blocker with a low affinity for beta₂-receptors in bronchial smooth muscle, blood vessels, and fat cells and no intrinsic sympathomimetic activity.</p>