AVIFLEX(Glucosamine 750 Tab)

<p style=\"text-align: left;\">  Store below 30 ^oC. </p> <p style=\"text-align: left;\">  Protect from light and moisture </p> <p style=\"text-align: left;\">  Keep out of rich of children.</p>

<p style=\"text-align: left;\">Contact a poison control center.</p>

<p>Breathing problems, tightness of throat or chest, chest pain, rash, itchy skin, vomiting, nausea, and stomach pain, constipation, diarrhea, loss of appetite, feel tired, headache.</p>

<p style=\"text-align: left;\">Medicines used to lower blood sugar, or to treat diabetes (examples: metformin, glyburide), Glynase, Micronase, pioglitazone), Blood thinning medicines, warfarin.</p>

<p style=\"text-align: left;\">Although no information is available on the effect of glucosamine on lactation, all manufacturers of this medicine advise avoiding the medicine during lactation. </p>

<p style=\"text-align: left;\">   FDA pregnancy category C</p>

<p style=\"text-align: left;\">If there is asthma or any kind of this disease</p>

<p style=\"text-align: left;\">Shellfish allergy, diabetes mellitus, kidney disease, liver disease, stomach or intestinal problem.</p>

<ul> <li style=\"text-align: left;\">Adult over 18 years: 500 to 750 mg twice daily. Treatment must be reassessed if no benefit is observed after 2-3 months.</li> <li style=\"text-align: left;\">Missing a dose: This is not harmful. If you miss a dose simply resume taking it on your previous schedule. Do not take double or extra dose.</li> </ul>

<p style=\"text-align: left;\">Symptomatic relief of mild to moderate osteoarthritis.</p>

<ul> <li style=\"text-align: left;\">Possible mechanism of action involves stimulation of <a href=\"http://en.wikipedia.org/wiki/Proteoglycan\">proteoglycans</a> synthesis and reduction of <a href=\"http://en.wikipedia.org/wiki/Catabolism\">catabolic activity</a> of <a href=\"http://en.wikipedia.org/wiki/Chondrocyte\">chondrocytes</a> resulting in the inhibition of  <a href=\"http://en.wikipedia.org/wiki/Protease\">proteolytic enzymes</a> production which contribute to cartilage matrix damage and cause death of articular chondrocytes.</li> <li style=\"text-align: left;\">Glucosamine is incorporated into the molecular structures of mucopolysaccharides, glycoproteins, glucosaminoglycans and proteoglycans, which are present in articular cartilage and synovial fluid.</li> <li style=\"text-align: left;\">Glucosamine balances the metabolism of joints, repairs the damaged joints and shows mild anti-inflammatory properties osteoarthritis.</li> </ul>